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アドレナリン投与時間の遅れが脳機能予後へ及ぼす影響の検討
https://kokushikan.repo.nii.ac.jp/records/12557
https://kokushikan.repo.nii.ac.jp/records/125576348e09c-5443-4276-98eb-8e3a4fa3b2e7
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
本文 (1.1 MB)
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| Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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| 公開日 | 2018-01-29 | |||||
| タイトル | ||||||
| タイトル | アドレナリン投与時間の遅れが脳機能予後へ及ぼす影響の検討 | |||||
| 言語 | ja | |||||
| タイトル | ||||||
| タイトル | The adverse effects of late adrenaline on neurological outcomes of patients experiencing out-of-hospital cardiac arrest | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | jpn | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | departmental bulletin paper | |||||
| 見出し | ||||||
| 大見出し | 原著 | |||||
| 言語 | ja | |||||
| 見出し | ||||||
| 大見出し | Original | |||||
| 言語 | en | |||||
| 著者 |
植田, 広樹
× 植田, 広樹× 田中, 秀治× 田久, 浩志× 匂坂, 量× 曽根, 悦子 |
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| 著者ID | ||||||
| 内容記述タイプ | Other | |||||
| 著者ID | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | J-GLOBAL ID : 200901068139604573 | |||||
| 著者ID | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | J-GLOBAL ID : 200901029664949748 | |||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | OBJECTIVE : Adrenaline is the only vasopressor that can be given in the event of out-of-hospital cardiac arrest (OHCA) according to the Japanese EMS protocol. However, there is little clinical evidence that adrenaline benefits long-term survival after OHCA. The aim of this study was to investigate the effects of early adrenaline administration by EMTs on favorable neurological outcomes among patients who experienced OHCA. METHODS : Potential subjects were a total of 822,250 patients who experienced OHCA between 2006 and 2012 and who were registered in a nationwide Japanese database. Subjects were 40,970 patients who received adrenaline prior to hospital arrival. The effects of the time from contact to the first administration of adrenaline (timing of the first administration of adrenaline, or TAA) on favorable neurological outcomes (a CPC score of 1-2) were evaluated as follows. Patients were divided into three groups based on the TAA (early group (n＝18,890：TAA < 7.6 min, intermediate group (n＝17,669) : TAA of 7.6 to 15.5 min, and late group (n＝4,411)：TAA > 15.5 min). Statistical analysis was performed using the crude odds ratio (OR) and 95% confidence interval (CI)． RESULTS : Patients in the early group served as a reference. In comparison to the early group, the intermediate group had an OR for a favorable neurological outcome of 0.48 and a CI of 0.40-0.58, and the late group had an OR of 0.24 and a Cl of 0.19-0.29. The early group had significantly improved outcomes (CPC score of 1-2) compared to the late group. CONCLUSION : Adrenaline administered by EMTs significantly improved neurological outcomes in patients during the early stages of OHCA. An exhaustive review of the adrenaline administration protocol for EMTs is needed to increase the likelihood of favorable neurological outcomes in who experiencing OHCA. |
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| 書誌情報 |
国士舘大学体育研究所報 en : The annual reports of health physical education and sport science 巻 35, p. 9-17, 発行日 2017-03-31 |
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| 出版者 | ||||||
| 出版者 | 国士舘大学体育学部附属体育研究所 | |||||
| ISSN | ||||||
| 収録物識別子タイプ | PISSN | |||||
| 収録物識別子 | 0389-2247 | |||||
| NCID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AN00089533 | |||||
| 論文ID(NAID) | ||||||
| 関連タイプ | isIdenticalTo | |||||
| 識別子タイプ | NAID | |||||
| 関連識別子 | 40021287081 | |||||
| NDC | ||||||
| 主題Scheme | NDC | |||||
| 主題 | 492.32 | |||||
| NDC | ||||||
| 主題Scheme | NDC | |||||
| 主題 | 492.29 | |||||
| フォーマット | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | application/pdf | |||||
| 著者版フラグ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
| キーワード | ||||||
| 主題 | paramedic, OHCA, time-limited effect, ROSC, favorable neurological outcomes at 1 month, early epinephrine administration アドレナリン投与, 救急救命, 脳機能障害, 社会復帰率, 心停止 |
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| 注記 | ||||||
| 値 | 表紙の表記 : 第35巻 (平成28年度) | |||||
